I would pass on the muley.  He's on to me by the looks of it and I wouldn't want to risk an iffy shot.  Full draw or not, he's going to move much faster than an arrow out of my longbow.

As for the antelope, he's dead.

By the way, this is a pretty cool thread and thanks for posting it.

I would have taken both shots in a heartbeat and tried for a couple of inches lower on each. Good ones!!

For the muley I would aim right where you have it. For the lope since his front left leg is back behind the shrub I would aim about an 1" or 2" behind your spot.

I'de shoot till I ran outta arras!

I would take both of those shots. I would just aim lower as has been said before in case they ducked.

Ryan frist things frist which side of the HWY is this mule deer on? It could make a big difference!    
Assuming it is on the right side of the road I might be one dot lower and 1/2 inch right.
The goat I would wait for a better shot because of the angle. I shot a antelope 1" to the right 1" lower than your dot and it only took one lung out. Luckly the arrow hit the offside shoulder dropping him in his tracks giving a second shoot for quick ending. If you aimed a little futher back it would work fine but will be a messy gut job.

If I wasn't so slow on my reply you would have answered my frist question!